How will it help me?
Reclast, like all bisphosphonates, increases bone density. It’s been shown to reduce the risk of fractures of the vertebrae (70% reduction), hip (41% reduction), and other bones, such as wrist (25% reduction), compared to patients not taking any osteoporosis drugs.
How would I take it?
Reclast is given via a 15-minute injection, once a year. In addition, it’s recommended post-menopausal women take a daily dose of 1200mg of calcium and 400-800 IU vitamin D3 throughout the year.
What are the common side effects?
The most common side effects of Reclast are flu-like symptoms: fever, muscle and/or joint pain, and headache. Less common side effects are severe bone and muscle pain; eye inflammation, and possible kidney damage. Uncommon though possible serious side effects include atrial fibrillation (irregular heart rhythm), and jaw damage. Your doctor may recommend you have a dental exam for preventive tooth and gum care before taking Reclast, as it can interfere with healing after a tooth extraction or other invasive dental procedure.
Boniva IV (ibandronate sodium)
Is it recommended for me?
Boniva IV received FDA approval for treatment of osteoporosis in post-menopausal women in January 2006.
How will it help me?
Boniva increases bone density throughout the skeleton. It’s been shown to reduce the risk of spinal fractures by about 50%, but hasn’t shown to be effective in reducing other fractures, such as hip or wrist.
How would I take it?
Boniva IV is given via a 15- to 30-second injection once every 3 months (four times per year).
What are the common side effects?
Common side effects of Boniva IV include headache, stomach upset, and flu-like symptoms: fever, chills, fatigue, and joint/muscle aches. An uncommon, though serious side effect is jaw damage. Tell your dentist if you’re going to take Boniva IV, as it may interfere with healing after a tooth extraction or other invasive dental procedure.
Bottom line
•Reclast is injected just once a year, vs. four times a year for Boniva IV.
•Reclast is effective against all kinds of fractures; Boniva IV is approved only for prevention of hip fractures.
•A rare side effect of Reclast is heart problems.
•Both Reclast and Boniva IV have been linked to serious (though very rare) jaw problems.

