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Wednesday, November, 11, 2009
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Fosamax, Actonel, Boniva: Why Might a Patient Be Prescribed One Oral Bisphosphonate Over Another?

Neil Gonter, MD
Neil Gonter, MD
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Internist, Rheumatologist

Neil J. Gonter, M.D., is a board certified Internist and...

Neil Gonter, MD

Wednesday, March 28, 2007
View All of Neil Gonter, MD's Posts
As you may be aware, there are currently 3 FDA approved therapies for osteoporosis.  I will try to give you the important differences in the drugs in order to allow you to make an educated decision on therapy.   Long-Term Experience:   The first drug approved was Fosamax, which was...
  1. Very Interesting
    Pam M
    Tuesday, September 11, 2007 at 11:01 AM
    Im pleased that these studies are getting some where because if it wasnt for the studies, we would not be were we are wih the medications. I think that the eople that make this happen for all of u are not credited enough!!! Thanks so much to everyone that tries to help us and thanks so much to you Lila for all of the great info... Love Pam xoxoHeart
    Reply
  2. Does Actonel really work better?
    Anonymous
    Tuesday, January 08, 2008 at 10:03 PM
    You said Actonel works on a lot more sites than the other drugs.  How does one bisphosphonate have the ability to selectively prevent fractures at various sites?  What were the parameters and selection criteria for the individual studies that showed this?  I still can't grasp how a bisphosphonate would selectively act on the spine and not have an impact on other skeletal sites.
    Reply
  3. Osteonecrosis
    Elma
    Saturday, March 15, 2008 at 10:35 AM
    I have taken fosamax for 5 years,I gave it up this winter when I read about the results of osteoecrosis of the jaw,just wondering what your thoughts are on this. Thankyou
    Reply
  4. Untitled Comment
    just switched to generic
    Saturday, April 05, 2008 at 02:49 AM
    If Actonel and Fosomax have different benefits why don't docs prescribe both and patient takes actonel one week and fosomax the nest?
    Reply
    re: Foszmax
    ukj763
    Thursday, January 22, 2009 at 08:10 AM

    I too, am giving up on Fosamax.  After 2 1/2 years, my bone density is Much Worse.!

    Reply
  5. Fosamax
    genecall
    Tuesday, April 29, 2008 at 12:47 PM

    Is'nt that nice,Neil Gonter is a paid hack for the pharmaceutical companies. I notice that he does not mention the number or substance of the law suits now pending in regards to Fosamax.

     

    I used Fosamax twice and had to discontinue after my joints stayed inflamed for almost 4 days. Had I continued I might have experienced further joint discomfort and bone loss in my jaws.

     

    Do not send me your crap in the future.  You do a great diservice to the community. PRINT THAT!!!

    Reply
    re: Fosamax
    Jamie
    Monday, September 15, 2008 at 11:15 PM

    I used Actonel twice and both times my joints became inflamed for a week.  I have made the decision to stop taking the drug and after reading your comment, I will do more research about the other possible side affects which they failed to mention in the warning pamphlet.

    Reply
    re: re: Fosamax
    gratefull lady
    Tuesday, June 09, 2009 at 10:18 AM

    When I began taking Actonel I felt like my joints became painful, but after a while I adjusted very well to this great product.  I took Actonel for some years and my bone density tests were much better than at the beginning of my treatment.  I stopped for a year and now I am back to the Actonel treatment again to prevent fractures. 

    Reply
  6. spelling
    WK
    Saturday, July 19, 2008 at 11:41 AM

    This is an informative article.  Thanks

    Please note in the third paragraph under clinical studies the word "humorous" should be spelled "humerus".   Smile

    WK

    Reply
  7. fosamax
    Geri
    Thursday, November 20, 2008 at 09:32 AM

    Is there a generic for this drug.  I understand the patent will be out in 2008.

    Reply
  8. Actonel
    Anonymous
    Wednesday, January 21, 2009 at 06:03 PM

    I am 29 years old and have been taking Actonel for almost three years. I am a female runner and after finding stress fractures in both of my legs at the same time my Dr. ordered me a bone density scan. It came back in the Osteopenia range very close to Osteoperosis. He was hesitant to put me on the Actonel since it is marketed for older women. I also take calcium vitamins, 2 a day and I get scanned every year. After almost three years my results have increased and my spine is very low in the normal range and my hip almost there. However after having a bone scan this past week a stress fracture was discovered in my lower leg.  This was very dissapointing to find that even on the medicine I am still getting fractures.

    Has anyone had any similar experieneces?

    Reply
    re: Actonel
    Miss
    Wednesday, July 08, 2009 at 03:30 PM

    Have you tried other forms of treatments, besides prescriptions.  The side effects of these drugs scare me.  It also worries me that these drugs inhibit the body from removing calcium it needs to function from the bones.  Your body will not use calcium from your diet, it has to take it from your bones.  Look up Osteodenx.  www.n-terminus.com

    Reply
  9. Actonel
    Elaine Luzansky
    Wednesday, February 11, 2009 at 11:11 AM

    I have been taking Actonel on and off for about three years.  However, I do take generic Prilosec due to heartburns every day.  Without that pill, I would suffer at night.  Now, back to Actonel...I asked my doctor about taking Actonel and he was sort of vague.  I stopped my Actonel because it states that with continuing heartburn, you should not take it.  Or is it if you take Actonel and you get a heartburn?  No answer to that...Asked the pharmacist and she was vague too.  I do not think they know enough about damage this pill can do.  So, I am not taking it anymore.  My mother had Osteo, now me and my daughter.  I guess it runs in families and there is nothing really one can do.  If you can, please reply....

    Reply
  10. generic Fosamax
    Margo Langley
    Saturday, July 04, 2009 at 08:37 AM

    My gyno prescribed Generic Fosamax, and I experienced the same aches and pains decribed by the Lipitor user (article in  News & Observer, 23 June 2009) It was uncanny - my symptoms began almost immediately after having taken the FIRST pill! After day 6 my problems eased. Nothing in the product information prepared me for what I went through. Do you think HRT may be a better solution for my osteoporosis?

    Reply
  11. Generic for Fosamax
    Janet
    Tuesday, August 04, 2009 at 07:18 PM

    I am 71 years old and my mother had osteoporosis, so my doctor has had me on Fosamax for about 6 years and most recently on the generic.  The bone scans I've had since on this drug show definite improvement and I see no different in either drug.  Both work great for me.

    Reply
  12. Boniva
    Anonymous
    Friday, August 21, 2009 at 10:32 AM

    I have taken Boniva for two years. Recently, last two months, I have had terrible heartburn, thought I was having a heart attack but relived by antiacids. My last dose was August 9, and my Jaw and mouth became sore. So I was taken off it.  Well

    yesterday I had a bone density test and Lo an Behold, I was worse than when I started Boniva, before I started test was 2.8 now after two years of Boniva it is 3.3.

    Can anyone explain this. I believe Boniva actually hurt my bones . Have you heard of this? I am totally defeated. I took it just as instructions said.

    Reply
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