Monday, November 10, 2008
Due to poor compliance issues with bisphosphonates, companies are working on new delivery systems that would cut down or eliminate the gastrointestinal and esophagus problems seen with these drugs.
For years, bisphosphonates have been the gold standard for osteoporosis treatment, but these medicatio...
Great explanation of a complex subject- And it's great news indeed for those who want/need to take a bisphosphonate but have had such awful gastro side effects. I hope they can get this technology from "bench to bedside" ASAP. - PJH
Hi PJ: Thanks for your kind words. Let's keep our fingers crossed that this will pan out sometime soon, since the Pharmaceutical Co claims that implementing this wouldn't require much financial outlay for the BP manufacturer's. Hopefully the award Merrion recieved will move things along faster. They were in Phase II trials over a year ago, but I'm not sure where it stands now. Since it seems like such a simple delivery system to apply to existing bisphosphonates, I can't see why others (drug co's) wouldn't embrace it considering the problem they are seeing with NON COMPLIANCE with these drugs. This system won't alleviate all the side effects, but it could certainly help with the most common GI problems, the drugs lack of absorption, and complex dosing regime.
Thanks again,
Pam