I have been taking Actonel (and for the last 6 months Foxamax) for over 5 years. As time passes, I seem to be getting more g/i upsets. I attributed this to food poisoning or inability to tolerate more than one glass of wine, but today in mentioning this to my doctor, she said I should not take Fosamax on an empty stomach. She said to eat first and then take it. Since this seems to be against the instructions on the drug, I would like to know if this will make Fosamax less effective? Also, will taking Fosamax with food cause more g/i distress rather than less?




