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Thursday, December 22, 2011 Ellen asks

Q: I would like to know risk/benefit of taking Forteo in case of autoimmune condition(Stil's desease)

and how Forteo affects liver health?
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Answers (2)
Pam Flores, Health Guide
12/22/11 4:45pm

Hi Ellen,  are you asking about a child with JRA?  If so, I'm not aware of children being able to take Forteo because it has never been approved for that population of patients.  If you are asking about yourself or another adult, here's some great info on Forteo, from the Cleveland Clinic.

 

This article is very good on Forteo and answers most questions, but I'm sure it doesn't include anything on Stils disease.  In any case, rheumatoid arthritis is a secondary cause for osteoporosis, so this may be why you're asking about it.  If you could provide more information, that would be great.

 

I took Forteo for 2 years and did very well going from severe osteoporosis -3.6 to -1.9 (osteopenia) in one year and maintained that fantastic gain for several years.  I'm still in the osteopenia range but at a slightly worse score, but not bad  (-2.3).  I also didn't have anymore fractures since taking it I had 6 spinal fraxs before I took Forteo.

 

I would definitely ask you Dr. about this medication in conjunction with Stil's disease.  If your doctor is recommending this he/she must know about all medical issues you are dealing with so please discuss this with whomever is rxing this medication.  You could also call the 800 number at Eli Lily and ask there, but when you do ask to speak to a nurse practitioner, if you decide to call.  Here's the number 866-4FORTEO

 

Good luck...

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Pam Flores, Health Guide
12/22/11 5:51pm

Hi Ellen, sorry I forgot about your liver question.  No specific testing has been done on Forteo and the liver.  However, here is some info on how it's metabolized that may help. 


Elimination

~~~~~~~~~~~~~~~~~
Metabolism


Metabolized by nonspecific proteolytic enzymes in the liver (possibly Kupffer cells).1
Elimination Route

 

Excreted via the kidneys.1


Half-life

Following sub-Q administration, approximately 1 hour.1  From Drugs.com

 

So it's metabolized by the liver and excreted by the kidneys within 1 hour after the injection.

 

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By Ellen— Last Modified: 12/22/11, First Published: 12/22/11