Generic Name: ESTRADIOL SEMIWEEKLY - TRANSDERMAL Pronounced: (ES-tra-DYE-ol) Vivelle-Dot TD Precautions
Before using estradiol, tell your doctor or pharmacist if
you are allergic to it; or if you have any other allergies. This product may
contain inactive ingredients, which can cause allergic reactions or other
problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
vaginal bleeding of unknown cause
certain cancers (such as breast cancer, cancer of the
heart disease (such as heart attack)
family medical history (especially breast lumps, cancer,
blood clots, angioedema)
blood clotting disorders (such as protein C or protein S
high blood pressure
high cholesterol/triglyceride levels
The beginning of summer kicks off the camping and hiking season, anxiously awaited by those who have endured a long cold winter. This year will likely prove to be one of the busier camping seasons as many Americans bypass more expensive vacations that involve pricey airline tickets or gas guzzling road trips. Emergency department staff will probably see a greater number of people with contact dermatitis caused by exposure to poison ivy, poison oak or poison sumac. Many people have never seen poison ivy , or perhaps wouldn't recognize it if they saw it. Poison ivy, poison oak and poison sumac belong to the plant genus Toxicodendron (previously referred to as Rhus ). Toxicodendron means "poisonous tree." These plants have an oil-based substance in the resin on their leaves and in their stems and branches called urushiol that causes a delayed skin reaction in about 50% of people that contact it. Urushiol may cause severe contact dermatitis in people that have previousl...
Osteolysis or bone loss after total knee replacement (TKR) can be a problem. Tiny flecks of bone and debris from the backside of the implant lead to osteolysis. Over time the implant can come loose or the bone can fracture. This study reports two changes that were made to reduce the risk of osteolysis. The first step was to polish the baseplate surface of the tibial (lower leg bone) implant. Before that a grit-blasted surface finish was used. The second step was to change the way the implant was sterilized. Before 1993 implants were sterilized with gamma radiation in air. Later this was changed to radiation in nitrogen or gas plasma. Results were measured by taking X-rays of the implants. The amount of osteolysis was measured. Knee alignment was also viewed. They found the amount of osteolysis was lowered from 34 percent to 6 percent when these two changes were made. Osteolysis was also more severe in the grit-blasted group. The authors report several other risk factors as well. For exam...
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