I also have acid reflux and had ulcers. With my doctor knowing my gastro situation, I was advised to take Actonel for osteoporosis. Therefore, last December, my doctor gave me four samples of the weekly actonel, and one sample of the monthly actonel. I was to take the weekly and then if I wanted to continue, try the monthly actonel.
I took the four weekly actonel from late December thru the third week of January. Upon taking the 2nd weekly dose (on Sunday), the following Tuesday I noticed I had more gastro problems, didn't feel too well, and diarrhea! These problems lasted for three or four days. I thought it was something I ate! Each of the next two weeks/doses, by the Tuesday following the Sunday I took the Actonel, I became sick again. And each time it was worse. At the end of the four weekly doses, I called my doctor because I was hesitant about taking the monthly dose. She encouraged me to proceed saying the reaction would probably subside. I took the one monthly dose, and it almost killed me! All of my gastro problems intensified ten-fold. I have been very sick for the last seven months. Yes, I have gotten somewhat better; however, at one point I was so sick my gastroenterologist did a endoscopy and discovered my esophagus was burned. He originally thought I had Barrett's Esophagus (sometimes a pre-cursor to cancer); however, a biopsy indicated I did not. It appears the actonel burned my esophagus.
I am still sick and wondering if this will ever go away. My doctor wants me to take an IV dose of Boniva (it misses the gastro area) but I am very hesitant. I understand the consequences of falling and breaking a bone with osteoporosis, but it looks either way I will become bedridden soon if I continue with osteo treatment, or if I fall. I haven't made a firm decision yet. I'm waiting for one more test to be completed before I decide, but I would not recommend anyone with gastro issues taking Actonel. Or any of those meds that indicate gastro problems are possible.