Merck, the manufacturer of Vioxx recently announced that preliminary analyses of its MEDAL (Multinational Etoricoxib and Diclofenac Arthritis Long-Term Program), show that patients with osteoarthritis and rheumatoid arthritis have similar cardiovascular outcomes between its experimental COX-2 inhibitor drug, Arcoxia, and diclofenac, a traditional nonsteroidal anti-inflammatory drug (NSAID). Merck is developing Arcoxia as the successor to Vioxx.
The MEDAL program is a group of three studies that...
- Find
Cox-2 Inhibitor Drug Interactions With Bisphosphonates
Featured Health Expert
More information on "Cox-2 Inhibitor Drug Interactions With Bisphosphonates"
From Our Experts
EXPERT
Cox-2 Inhibitors, and Why We Miss Them
By Dr. Mark Borigini, Health Expert
When Cox-2 inhibitors first came on the market there was almost euphoria. Finally, those patients with chronic pain and in need of... Read more »
EXPERT
Celebrex and COX-2 Inhibitors vs. Anti-Inflammatories
By Dr. Mark Borigini, Health Expert
A couple of months back I wrote a post discussing the concerns I and many others have regarding the return of severe gastrointestinal side... Read more »
EXPERT
Update from the American College of Rheumatology: Cox-2 Inhibitors...
By Mark Borigini, M.D., Health Expert
When Cox-2 inhibitors first came on the market there was almost euphoria: Finally, those patients with chronic pain and in need of... Read more »
EXPERT
Cox-2 Inhibitors Revisited, Again
By Mark Borigini, M.D., Health Expert
A couple of months back I wrote a blog discussing the concerns I and many others have regarding the return of severe gastrointestinal side... Read more »
EXPERT
Oral Bisphosphonates Fosamax, Actonel, Boniva and Side Effects:...
By Rose Chon, Health Expert
Treatments for osteoporosis include a variety of medications (bisphosphonates, estrogen/hormone therapy, selective estrogen receptor... Read more »
From Our Sources
Clinical trial: COX-2 inhibitor study in patients with RA
This is a study to find out if an investigational drug called GW406381 can help people with rheumatoid arthritis. This international study is... Read more »
Clinical trial: Efficacy and safety of investigational COX-2 i...
GlaxoSmithKline is conducting a clinical trial to see if its investigational drug, a COX-2 inhibitor called GW406381, is safe and effective. This... Read more »
Data on COX-2 inhibitor Arcoxia gives good--and bad--news
A new study on the COX-2 inhibitor Arcoxia is intensifying worries about the drug's safety. Though researchers found that the new drug had similar... Read more »
Data on new COX-2 painkiller set to be released
Results from a large study on Merck's new COX-2 inhibitor drug, Arcoxia, are about to be released. Many doctors and patients are awaiting the results... Read more »
Scientists discover why COX-2 inhibitors are bad for the heart...
U.S. and Canadian researchers have discovered why COX-2 inhibitors like Celebrex cause blood-pressure and heart problems. The researchers also found... Read more »
Featuring Content From:
By using this service, you accept our Terms of Use. Please read them. The consumer health information on is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. Copyright © 2012 Remedy Health Media, LLC. All Rights Reserved.
