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Red Clover

Posting Date: 07/29/2002

A double-blind controlled trial published in the Journal of Clinical Endocrinology and Metabolism (March 1999) demonstrated that red clover isoflavones help keep large blood vessels pliable.

Dose

The usual daily dose contains 40 mg standardized red clover isoflavones. It may take four to six weeks to get the full benefit.

Special Precautions

Pregnant women should not take red clover products until further tests determine whether this is safe. Isoflavones have estrogen-like effects, and estrogens are not recommended during pregnancy.

Adverse Effects

No adverse effects of trifolium isoflavones at the recommended dose have been reported. Blood biochemistry was monitored in some studies and showed no significant changes.

Possible Interactions

No interactions have been reported. It seems illogical, however, to mix Promensil with standard HRT regimens or oral contraceptives, and in theory these compounds could be incompatible.

A red clover extract containing coumarin derivatives might in theory interact with the anticoagulant Coumadin. Close monitoring of prothrombin time or INR is advisable.