People's Pharmacy

Premarin

Generic Name:conjugated estrogens

Revised:4/1/2000

Table of Contents

Special Precautions

There are a number of situations where Premarin may be inappropriate. Pregnant women should not use this medication, as it could affect the fetus.

Women with a history of breast cancer or other malignant disease susceptible to estrogen are generally advised to avoid this hormone.

Blood clotting disorders such as thrombophlebitis are also a reason to be wary of Premarin.

Prolonged use of postmenopausal estrogen has been controversial because of questions about cancer.

Endometrial carcinoma or cancer of the uterine lining is more of a risk for women exposed to estrogen. This adverse reaction may be counteracted by simultaneous administration of progestins.

Vaginal bleeding could be an early warning sign of cancer and requires immediate medical attention.

The risk of breast cancer is more uncertain. Studies have provided conflicting results, and more research is needed. Women with a strong family history of breast cancer will want to discuss this issue with their doctor.