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Drug Library

Zoloft

Generic Name:sertraline

Revised:4/1/2000

  Table of Contents
  • Overview
  • Side Effects and Interactions
  • Taking the Medicine
  • Special Precautions
  •   Special Precautions

    Some people may need very close monitoring if the doctor prescribes Zoloft. For people who have had an episode of mania, there is a risk that manic symptoms could be triggered by Zoloft.

    In rare cases, Zoloft has led to significant weight loss. This may be a problem for an underweight person.

    Because Zoloft may cause drowsiness or dizziness, people taking this medicine should not drive or use dangerous machines unless an objective evaluation shows they are not impaired.

    People with liver problems or kidney disease may need to start on a reduced dose, as they may eliminate Zoloft less efficiently than otherwise healthy people.

    Anyone with a history of suicide attempts must also be extremely vigilant. There have been reports that some people may develop a preoccupation with suicide or violence while taking Prozac.

    It is still not certain whether this is caused by the underlying mental condition or is in some way related to the drug. If Prozac were responsible for any of these incidents, there might also be a risk with Zoloft.

    Family members should help monitor people on Zoloft for suicidal thoughts or self-destructive behaviors. The doctor must be notified immediately in such cases.

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