People's Pharmacy

Serzone

Generic Name:nefazodone

Revised:4/1/2000

Table of Contents

Side Effects and Interactions

Side effects associated with Serzone include drowsiness, dizziness, lightheadedness, weakness, dry mouth, insomnia, nausea, constipation, digestive tract upset, confusion, forgetfulness, agitation, visual disturbances, ringing in ears, increased appetite, and infection.

Less common adverse effects that have been reported include a decrease in heart rate, eye pain, lowered libido, impotence, unusual ejaculation, loss of orgasm, difficulty concentrating, flu symptoms, thirst, incoordination, cough, urinary difficulties, rash, itching, lowered hematocrit, liver test abnormalities, hangover effect, unsteadiness, hallucinations, breathing difficulties, and suicidal thoughts. Report any symptoms to your physician promptly.

Serzone interacts with a number of other medications.

Anyone taking certain antidepressants, especially drugs such as Nardil or Parnate, should stop such a medicine at least two weeks before starting on Serzone.

If Serzone was taken first, one week should elapse before starting on one of these other medicines. This interaction could be life threatening.

Three other medications that could be extremely hazardous in combination with Serzone include Seldane, Hismanal, and Propulsid. Irregular heart rhythms or cardiac arrest are possible consequences of such an interaction.

Xanax (alprazolam) and Halcion (triazolam) are both affected by Serzone. Blood levels of these drugs may increase dramatically and pose a significant hazard, especially for older people. Haldol (haloperidol), Inderal (propranolol), and Lanoxin (digoxin) may also be affected by Serzone.

Check with your pharmacist and physician before taking any other medicines.