Information and opinions on health from Sam at HealthCentral.com. HealthCentral.com is one of the top health destinations on the Web, with more than 35 condition-specific, wellness and general health Web properties. http://www.healthcentral.com/profiles/c/697221/index http://www.healthcentral.com/profiles/c/697221/rss self application/xml en-us 15 120 19 http://www.healthcentral.com/images/hc_logo_sm.gif http://www.healthcentral.com/profiles/c/697221/index http://www.healthcentral.com/chronic-pain/c/697221/104929/successful Fri, 26 Feb 2010 06:15:20 -0500 Sam I recently replaced the generic extended-release (ER) Oxycodone with the immediate release (IR) Oxycodone. Daily mg’s are the same. I am failing to reproduce the effective coverage obtained with the ER. Now, pain is intensified, mobility is strained, depression is great and restful sleep is nonexistent. Has anyone been successful exchanging an ER opioid with an IR opioid?   Reason for the exchange: Pharmacy restock orders went... http://www.healthcentral.com/chronic-pain/c/697221/104929/successful