Biopsy harmful?

I am 51 years old and in excellent health.  My father had prostate cancer in his mid 60s.  My PSA is very low, 0.5, but in a DRE my doctor detected that one side of my prostate was larger than the other.  I have no symptoms whatsoever and enjoy an active and fulfilling sexual relationship.  He recommends a biopsy as soon as possible.  I have concerns.  I have no fear of any temporary pain or discomfort of the procedure itself.  My concern is that I find it hard to believe that poking multiple holes in the prostate does not in some way inflame, irritate, weaken or damage it in some way.  This procedure is scheduled for tomorrow, so any quick advice would be much appreciated.