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Is My PSA Level Normal? The absolute value of PSA has been the long-term standard of care to determine whether one’s PSA elevation is significant. Previously, the magic number of “4” was defined as being the upper limit of “normal.” However, this may not be a good rule of thumb since approximately 15% of prostate cancers can occur in men with a “normal” PSA. When interpreting a PSA value, several factors need to be taken into consideration—not just the absolute value of the PSA. Some of these factors include: Age adjustment of the PSA PSA density Percent free PSA PSA velocity Age-Adjusted PSA Recent data has redefined the way that urologists look at PSA, and what is considered a "normal" PSA. Age-adjusted PSA values take into account that a 40-year-old should not have the same PSA as an 80-year-old. Accepted age-adjusted PSA rates are below 2.4 ng/ml for men under...
Dear Dr. Motola,
Four years ago I had surgery for a left inguinal
hernia, which unfortunately resulted in uncorrected internal post-op bleeding
causing ischemia and subsequent atrophy to the left testicle. Until
recently, I've never had my testosterone level checked against the reference
range. I am 83 years old and in very good health. I am told the normal
reference range is 200 to 900, hence my question ... is 259 good or bad
and is it dependent upon both testes functioning? My PSA level averages
3.5 and DRE tests are always normal. I have BPH . I am sexually active but not
as frequently as in the past.
start to fall after age 40. Symptoms
associated with decreased levels include memory loss, mood changes, depression ,
increased fat mass, loss of muscle mass, and a decrease in sexual function. These
symptoms are also associated with the aging process. Many times patients may
experience some of these symptoms, h...
At What Age Should I Start Getting PSA Tests? The age at which one should first have a prostate cancer screening has been debated. The recommendations of the American Cancer Society are for all patients over the age of 50 to undergo digital rectal examination and PSA testing . However, few weeks go by in the office without a patient under the age of 30 who requests a prostate cancer screening. Using 50 as an arbitrary age cut-off is subject to much discussion. Patients who are at high risk for prostate cancer – such as African-American men or those with a strong family history of a father or brother who were diagnosed with prostate cancer prior to age 65 – should begin screening at age 45. Prostate cancer is the second leading cause of cancer death in African-American males. African-American males have a 60% higher incidence of prostate cancer as well as a higher death rate from prostate cancer than white males – 64% vs. 26.2% according t...
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