Wednesday, May 30, 2012
Monday, January 04, 2010 Nefertiri asks

Q: recurrence of prostate cancer, prognosis.

In Jan 2007, my 76 years old father was diagnosed with aggressive prostate cancer (PSA 197, Gleason 9 (4+5), no tertiary pattern.  Ultra sound says "Prostate 100gram would account for PSA of 12.1 but not 197".  Metastasis not seen but presumed for treatment purposes  Note says "lymph/vascular invasion: suspicious but not confirmed " This was treated with external beam radiation (about 5 -6 months, 43 sessions) and hormone therapy (ongoing to present).  PSA dropped below 1 post treatment for 18 months and then started rising over 6 months, now at 7 or 9.   Is this a likely recurrence?  Or possibly OK as long as PSA is under 12.1?

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Jay Motola, Health Pro
1/10/10 9:44am

This most likely represents a recurrence of the disease.  Given the high gleason score, and the original PSA, it is extremely likely that at the time of the orginal diagonsis there was already disease that was outside of the prostate.  Depending on your dads overall health and rate of rise, there may be a role for the use of LH/RH agents.

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By Nefertiri— Last Modified: 05/05/11, First Published: 01/04/10