Chemist verifies partial inactivation of Flomax by beer. A second physiological test was made concerning the possible interaction of beer and Flomax seven days after the first serendipitous observation of such an effect, i.e., on the day of the 14th daily dosage of Flomax CR (0.4 mg), no beer having been consumed prior to going on Flomax or apart from the two reported incidents. The test was made with a smaller amount of beer (225 mL, 5.0% alcohol) taken during a supper of pasta around 7:15 PM preceded by a bowl of soup (200 mL) and concluded with black tea (200 mL). By 7:30 PM (15 minutes after the beer), 252 mL urine were voided (the previous voiding had been 309 mL at 1:15 PM), and the only voiding before retiring was 129 mL at 10:25 PM. At 11:00 PM, the 15th Flomax tablet was taken with the usual 180 mL water, but no urge to void was sensed until 6:10 AM when 712 mL urine were passed. From the time of drinking only 225 mL of beer until 6:10 AM, i.e., 11 hrs less 5 minutes, only 129 mL of urine was passed before sleeping; hence even a partial beer appears to exert a neutralizing effect on the function of Flomax to facilitate urination over a period of a few hours. It is noteworthy that the package information provided by Boehringer Ingelheim (manufactured by Astellas Pharma Europe B.V., The Netherlands) makes no mention of beer or alcohol interaction with Flomax or any mention of reduced efficacy arising from such consumption!