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Q: can you have a free-to-total psa reading of 10 and a regular psa reading of 2.5
You would not get a free PSA number with a total PSA number below 4 or above 10. The free % number is accurate and valid only for total PSA numbers between 4 and 10. If your total PSA is between 4 and 10, you would want a higher number, usually stated as greater than 25%. A lower number (below 25%) would be a concern and a urologist would have to advise on the next step to take. By the way, the free PSA would be given as a number and also as a percent, the % number being the key indicator.
The speed or velocity of the rise of total PSA over time is perhaps more important than the actual number. Some studies show the speed of the rise is more important than the actual PSA number. UroToday is a good site to check out as well as www.urologyhealth.org.
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