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Thursday, November 12, 2009
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Macrodantin Oral

Precautions and Side Effects


Generic Name: NITROFURANTOIN - ORAL
Pronounced: (NYE-trow-fyour-AN-toe-in)

Macrodantin Oral Side Effects

Table of Contents

Nausea, vomiting, loss of appetite, headache, dizziness, or drowsiness may occur. Take this medication with food to help minimize nausea. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

This medication may cause your urine to turn dark yellow or brown in color. This effect is harmless and will disappear when the medication is stopped.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This drug may infrequently cause very serious (rarely fatal) lung problems. Lung problems may occur soon after starting the medicine or after long-term use. Seek immediate medical attention if you notice any of the following unlikely but very serious side effects:

  • chest pain
  • shortness of breath
  • unusual/persistent cough


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • new signs of infection (e.g., fever, persistent sore throat)
  • easy bruising/bleeding
  • mental/mood changes
  • persistent or severe headaches
  • vision changes


This drug may rarely cause serious (possibly fatal) liver disease, blood or nerve problems. Tell your doctor immediately if you notice any of the following rare but very serious side effects:

  • persistent nausea/vomiting
  • dark urine
  • yellowing of eyes/skin
  • unusual/persistent fatigue
  • fast/pounding heartbeat
  • numbness/tingling of the arms/legs
  • muscle weakness


This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop:

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