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Sunday, November 22, 2009
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Zoladex SubQ

Precautions and Side Effects


Generic Name: GOSERELIN - INJECTION
Pronounced: (go-SIR-eh-lin)

Zoladex SubQ Side Effects

Table of Contents

Hot flashes (flushing), dizziness, headache, increased sweating, decreased sexual interest/ability, trouble sleeping, nausea, change in breast size, or mental/mood changes (e.g., depression, mood swings) may occur. In women, vaginal dryness may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • vaginal burning/pain (in women)
  • pain during sex (in women)
  • breast pain/tenderness
  • new/worsening bone pain
  • new broken bone
  • fast/irregular heartbeat
  • burning feeling in feet/toes
  • swelling of the ankles/feet
  • unusual tiredness
  • frequent thirst/urination
  • change in the amount of urine


Seek immediate medical attention if any of these rare but very serious side effects occur:

  • chest/jaw/left arm pain
  • trouble breathing
  • confusion
  • vision changes
  • slurred speech
  • weakness on one side of the body


Rarely, a very serious problem with your pituitary gland (pituitary apoplexy) may occur, usually in the first hour to 2 weeks after your first dose of this medication. Seek immediate medical attention if any of these very serious side effects occur:

  • sudden severe headache
  • mental/mood changes (e.g., confusion)
  • vision changes
  • vomiting
  • fainting


In men using this medication for prostate cancer, a rare but very serious urinary blockage problem or spinal cord problem (compression) can occur, especially during the first month of treatment. Tell your doctor immediately if you experience any of the following serious side effects:

  • severe back pain
  • numbness/tingling/weakness of the arms/legs
  • inability to move
  • painful/difficult urination
  • blood in the urine


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. In the US, you may report side effects to the Food and Drug Administration (FDA) at 1-800-FDA-1088.

In Canada, you may report side effects to Health Canada at 1-866-234-2345.

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