Prostate cancer is a hormonally responsive cancer. In 1966, Charles Huggins was awarded the Nobel Prize in Physiology or Medicine for work that began in the 1940’s with his colleague CV Hodges. Their work was able to establish that if androgens (testosterone) were eliminated in patients with prostate cancer, the cancer cells would atrophy.
The vast majority (95%) of androgen is testosterone and it is predominantly produced by specific cells in the testes known as Leydig cells. 5% of...

