Prostatic Intraepithelial Neoplasia

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Definition

Multiple endocrine neoplasia (MEN) type I is an inherited disorder in which one or more of the endocrine glands are overactive or form a tumor. Endocrine glands most commonly involved include:

  • Pancreas
  • Parathyroid
  • Pituitary

Alternative Names

Wermer syndrome; MEN I


Causes, incidence, and risk factors

MEN I is caused by a defect in a gene that carries the code for a protein called menin. The condition causes tumors of various glands to appear in the same person, but not necessarily at the same...

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