Tumors: Any T, Any N, M1, Any G (stage D2) Treatment Options. Hormonal therapy, which may be one of the following: orchiectomy alone or with an antiandrogen; LHRH agonists, such as leuprolide; leuprolide plus an antiandrogen; estrogens. Cure is rare in these patients but striking subjective or objective responses to treatment occur in most patients.
- Treatments for Urinary Tract Symptoms. External beam radiation therapy. Hormonal manipulation. Transurethral resection of the prostate (TURP).
- Treatments for Symptoms of Bone Metastasis. Radiation therapy (external beam radiation or strontium-89 radioisotopes) or hormonal manipulation (orchiectomy or LHRH agonist drugs or both).
Pain Relief. Low-dose prednisone (a corticosteroid) alone or with mitoxantrone reduces inflammation and may help relieve pain.
Recurrent Prostate Cancer
Treatment Options. Dependent on various factors: prior treatment, site of recurrence, coexistent illnesses, and individual patient considerations.
- Patients whose cancer recurs locally after prostatectomy: radiation therapy, hormonal therapy
- Patients whose cancer recurs locally after radiation therapy: hormonal therapy, prostatectomy (very select patients)
- Patients whose recurrent cancer has spread: See treatment options for stage IV
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