Hi everyone,
I was diagnosed with R/A 3 years ago, and after all the treatment and meds I now find myself in even more pain than ever.
I am working my way up to 20mgs Methotrexate in the usual weekly fashion. At present I am taking 12.5mgs via subcut injection, however after my last 2 jabs, I found my pain increasing severely - even in areas that had never been affected before. I had my jab on Wednesday last, and I have not been able to get out of the house since, mainly because I find it soooo difficult to walk or even to get shoes on. My hands and neck are also so much more painful than normal, and my new pain is in my jaw. I asked my doctor if this was normal to feel so ill, when this "wonder drug" is supposed to do the opposite. He didnt know the answer to my question and advised me to ask the rheumy clinic I attend. They say they have never heard of this happening, but to continue with the Methotrexate as before. I go for my jab tomorrow and I am anxious about how it will affect me for another week.
I would like to ask if anyone out there has had the same experience?
Many thanks
Debs


Debs, I am sorry to hear that you are having so much pain, and so many problems with your methotrexate. I too have experienced some of the problems that you have experienced while on the methotrexate. I have now been on methotrexate for 3 years at a 25mg a week dosage. And while it now is a necessity in my life I didn't always feel so positive about it. For the first year I experienced almost all the side effects that you can experience on methotrexate including the increased joint pain, I lost my hair from my forehead all the way to the very top of my head (which doesn't happen often), mouth ulcers, dizziness, and nausea. While I am not a doctor so I can't tell you for sure that things will get better, I can say from my personal experience that they have for me. Now, instead of having 7 bad days a week, I have 3-4 which is how long it takes me to recover from my methotrexate. I did some research for you and here is a link that tells a little bit about the side effects that you are experiencing:
http://www.healthcentral.com/rheumatoid-arthritis/c/53/7692/side/
Keep your head up and please know that we are all here for you if you have any questions or just want to vent. Good luck, and best wishes!