Hello Sharte, I was just reading your story and I have lived with RA for 10 years and Im only 35 years old.. I have taken two different TNF drugs, Enbrel and Humira. I started off taking methotrexate and planquenil, they did very little for me and then I changed Dr.'s and he suggested that I try one of the new TNF drugs so I did. I started taking Enbrel about 6 years ago and felt wonderful for about 5 years and than about 6 months ago the pain was back again so I just started taking Humira about 3 months ago and still do not feel near as good as when I first started on Enbrel. I have not had any side effects that I can see right now but I look it as I would rather enjoy the years that I have now when my kids are young and pray that they come up with a cure for my future..The part about giving my self shots , it's not the easiest thing to do but the benefits of it pay off. I hope this has helped you some..
I was diagnosed with RA April 2008, I am 54 years old. I now know I had RA many many years ago, I think in my early twenties. I have rhuematoid nodules (on my elbows, and feet) have had these for many many years, they were just never diagnosed as such. I also was told I had burnout about 8 years ago, working a full time job, doing university at night, single parent, exhausted most of the time. I finally changed doctors. I am lucky I have a good rhuematologist now. I have had no negative side effects from this medication, and I do believe the benefits outweigh the risks. My rhuemy says my RA is moderate which is a 3 on a scale of 1-6. From what I have read, I think mexotrexate is the same as methotrexate, is this correct?
Wow, you have been through so much on your journey. And you are right when you say no one understands because they can't see your pain. I couldn't have described that better! Even others with RA can't fully understand your pain, because everyone is different. But I can say I identify with you. My story played out quite a bit like yours with the diagnosis and having to admit to myself that I could no longer work, even though I tried so hard for quite awhile. When I try to explain my pain to my friends and family I tell them that it felt like every bone and joint in my body was broken. That is exactly how it feels to me. I often tell people that it seems like RA only effects the strongest ones, and that's how it sounds in your case as well. It's almost like it's lifes way of forcing us "Superwomen and Supermen" to slow down. I understand a little bit on how you feel about the biologics. You have to be able to have some control in your life especially after RA has taken control of so much as it is. I have attached some links on the studies of biologics. I hope this helps. Please don't think I am trying to push you into biologics, as I completely understand your position on them.
http://www.healthcentral.com/rheumatoid-arthritis/c/53/1832/orencia/
This link is for Orencia, which has less side effects than most of the biologics
http://www.enbrel.com/ra/clinical-experience.jsp
This site tells about the long-term experience of Enbrel
If you would like me to do further research perhaps on humira or remicade, let me know and I can get you some sites on that research as well.
Keep your head up, and please know that we are all here for you whenever you have questions, need advice, or just plain need to gripe. Good luck, and best wishes!