-
Untitled Comment
Lene Andersen
Wednesday, June 24, 2009 at 11:38 PMre: Untitled Comment
Ellen
Thursday, June 25, 2009 at 09:28 AMI understand your reservations and don't deny any of that. What concerns me is that, for people that have NOT found relief through very expensive medications like the biologics (and there are some on this site), that they might not be aware of something else that might help. There was a study done, and it didn't turn out well, but (as with the guaifenesin I take for FM), if the doses have to be so individually tailored that "one size doesn't fit all", it makes it harder to work with a large double-blind study. There are so many different kinds of arthritis, and probably the reason the cause isn't known is because there are multiple causes, and interactions between the causes.
Discovery Health Channel told the story of an outbreak of salmonella in the northwest US - it stemmed from tainted milk that ended up in ice cream, because one milk truck didn't sterilize the tank between shipments (they only washed it). Out of the many people who were affected, 3 teens ended up with permanent arthritis , affecting both joints & organs, because they had a genetic mutation that made them particularly susceptible to the salmonella bacteria.
I've talked with two people in New York State that are on antiobiotics for rheumatoid arthritis (both sero-negative, which might be noteworthy), and very happy with it. There are also people who either have had cancer and can't take medications like the biologics (or other reasons, I guess, like congestive heart failure), or who don't have the ability to pay for them. I don't think any options should be left unexamined in situations where people are unable to function.
There's a lot more written about this that involves much more than autoimmune diseases, such as cancer. It's known that cancer can be triggered by viruses, and possibly bacteria as well. Not all of it has been elaborated because it's very hard to detect the bacteria, they can morph into group form and films which don't respond like the individual cells. But it's worth lookin into. One book is Cell Wall Deficient Forms: Stealth Pathogens, Fourth Edition (Hardcover) by Lida H. Mattman.
re: re: Untitled Comment
Lene Andersen
Thursday, June 25, 2009 at 11:02 AMThis is fascinating. I had a chat with Google and found this page with more on antibiotic treatments. Seems that antibiotics can be helful for mild to moderate RA. I'm definitely going to ask my rheumatologist about this the next time I see her, just for research purposes.
As far as the user from Spain, she was asking about antibiotic treatments as that's what her doctor had prescribed. Nothing much beyond that.
good link!
Ellen
Thursday, June 25, 2009 at 11:32 AMThat's great that you found that page! A much more comprehensive summary than I could give, or had available off the top of my head. The Dr. Brown mentioned is the one referred to in the book I mentioned (The New Arthritis Breakthrough), and I had forgotten the term mycoplasma. He was apparently quite successful at treating patients with antibiotics.
more on mycoplasma
Ellen
Thursday, June 25, 2009 at 11:40 AMI just remembered another line of thought & research on this. One of the people I've personally talked with on the phone about the treatment, mentioned a site called www.cpnhelp.org. One of the organisms they've found is Chlamydia pneumoniae (not the STD-type Chlamydia, this is one that affects the lungs, hence "pneumoniae"). She had her doctor get in touch with one of the main researchers to find out how to get her started on this, what tests to do, etc., and she's very positive about it.
Since I had had pneumonia about 2 years before I was diagnosed with RA, I am kind of interested in this connection. When the RA fatigue first hit (I was told it was just Fibromyalgia at that point, since the joints weren't obviously involved, and I had had a lot of tendinitis too), one thing I said to my doctor was, "I've never had this kind of fatigue, except when I had pneumonia" even though I didn't have pneumonia by that time! But I had just had a colonoscopy, and I also wonder about the side effects of clearing out all the good digestive bacteria, along with the drugs I was given for sedation, etc. I wasn't using yogurt or anything at the time, and also was feeling overwhelmed with emotional stress for unrelated reasons. (I was also having difficulty swallowing, due to an esophageal stricture.) I've had a colonoscopy since, without those problems, thank Goodness!
-
minocycline on ACR website
Ellen
Thursday, June 25, 2009 at 10:01 AMI went to check if minocycline is actually on the website of the American College of Rheumatology. It is listed in the PDF document with the most recent recommendations of treatment for RA with DMARDS and biologics in the tables and text on pages 772-773 (when to use or not use), and it appears that minocycline should be avoided if there is liver damage or liver disease. If anyone is interested, here is the link:
http://www.rheumatology.org/publications/guidelines/raguidelines02.pdf
You will have to scroll to page 772-3 (or jump to the actual pages 11-12 of the posted document).
Minocycline is one of the tetracycline class of antibiotics, and the one most commonly used, apparently.
- Font size
- Email This
- Bookmark
- Thank you for your input
- Save
- RSS
- Report Abuse











I've seen the study before and there are some major problems with the methodology of it.
As far as I know, antibiotic treatment was used in the past when there were no real treatment options and I once answered a question from somebody in Spain who was on an antibiotic treatment for RA, so it sounds like different areas of the world may still be using it. If it can help somebody who hasn't responded to other treatment or who's had severe side effects preventing them from taking e.g., immunosuppressants, then sure,it may be better than nothing, but I would like to see an actual study that's been properly designed, rather than self-selected respondents replying to an Internet survey. The idea of judging efficacy of a treatment through a survey rather than a clinical study automatically makes the results suspect. Furthermore, the survey being commissioned by a foundation dedicated to "supporting antibiotic treatment for RA" makes big red flags jump up in my head.
As you, I would be very interested in hearing more about this from people who are taking antibiotics for RA. However, as I mentioned above, the only person I've ever run into who does this was the person in Spain. I think the fact that it appears that hardly anyone is receiving this treatment probably speaks volumes in terms of its real efficacy.