Curious...am HLA -B 27 positive for yrs. have osteoarthritis and countless surgeries for bone spurs and bone on bone. My neck is crumbling, especially for a 43 yr. old. Recent blood test showed an actual number on the Rheumat factor. Fortunately, it was in the normal range. My question is, does everyone have the Rheumat factor in their blood and it becomes diagnostic when the level is high? Or is having the factor in your blood suspicious of Rheuamtoid arthritis? I'd swaer that my Rheuam factor had always read "negative". I kinda a feel like my Rheumy is not doing enough to keep me from getting worse. He just gives me anti-inflammatories. I saw my mom have a shoulder, a large metatarsal bone and a collarbone get reabsorbed from severe arthritis which remained undiagnosed until it was too late. She had SEVERE Psorasis that got into her bones, ostoearthritis and a weakly posisitve ANA but never heard about her RH factor. These tests were done in the early 80's and I rememeber they were thinking she had lupus because her kidneys were quitting. I just don't want to end up like her. Her last year were spent on dialysis and oxycontin and vicodin and then dying at age 66. i remain positive, very active with work and bike riding and some weight lifting. I'm as proactive as I can ever and keep a very positive attitude. Sometimes I think my "sunny" disposition doesn't always do me justice when I see the Rheumy. I tend to downplay my pain which limits me at times and causes alot of sleep loss.