Rheumatoid Arthritis - All SharePosts Relating To "TNF-inhibitors"

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Christine Miller

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In Remission from JRA, Active April 2006 to February 2009

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posted 09/05/2008, comments (2)

New FDA Warnings for TNF Inhibitors- What are the Fungal Diseases Involved?

What are the warnings? The U.S. Food and Drug Administration just announced that the manufacturers of Humira, Cimzia, Enbrel, and Remicade must strengthen the existing “Black Box” warnings because of the risk of developing opportunistic fungal infections. These warnings are located in the Warnings and Precaution sections of the... Read more Chevron

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Christine Miller

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In Remission from JRA, Active April 2006 to February 2009

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posted 07/05/2008, comments (3)

New Rheumatoid Arthritis Treatment Guidelines

The American College of Rheumatology recently issued new guidelines for rheumatologists to use in their patient treatment decisions about the use on non-biologic and biologic disease modifying anti-rheumatic drugs (DMARDs). The recommendations and guidelines were published in the June issue of the journal, Arthritis Care &... Read more Chevron

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Christine Miller

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In Remission from JRA, Active April 2006 to February 2009

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posted 07/02/2008, comments (0)

TNF-alpha inhibitors may prevent kidney cysts

New research published online in June in the journal "Nature Medicine" finds that the TNF inhibitor etanercept (Enbrel) may offer treatment and hope to people with autosomal dominant polycystic kidney disease (ADPKD). ADPKD is a genetically inherited renal disease that... Read more Chevron

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Christine Miller

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In Remission from JRA, Active April 2006 to February 2009

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posted 06/20/2008, comments (0)

Golimumab Phase III Clinical Trials Show Promising Results

Centocor, a pharmaceutical company, issued two press releases on June 11, touting the positive results of its new TNF-inhibitor drug golimumab in three separate Phase III clinical trials. The results of the trials may help Centocor and Schering-Plough (working together to develop and market the drug) to move closer to receiving FDA approval... Read more Chevron

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Mark Borigini, M.D.

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posted 06/16/2008, comments (0)

Enbrel and the Mystery of the Black Box Warning

No, this is not the title of a Nancy Drew novel that begs solving. But I have had many patients asking me about the significance of the black box warning on Enbrel. And why was there no black box warning before this? Well, to review the facts of this case, up until recently, Enbrel was alone among the anti-tumor necrosis... Read more Chevron

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