Disease-modifying anti-rheumatic drugs (DMARDs) slow the advancement of rheumatoid arthritis. They reduce inflammation and joint damage. Taking DMARDs may lead to a remission. Common DMARDs include methotrexate (Rheumatrex), sulfasalazine (azulfidine) and lefluenomide (Avara).
Dear Dr. Borigini, I have been living with RA for about 8 years, diagnosed at age 25. I have been taking methotrexate and having good results with this treatment. My frustration however, is two fold. I have been unable to lose weight or to lower my cholesterol despite diet and exercising regularly. Can methotrexate can cause these two side…