Wednesday, May 19, 2010 Impulze, Community Member, asks

Q: Can Humira slow bone healing after a fracture/break?

Hi, I am a 32 yr old male who was finally diagnosed wit AS after 12 yrs of suffering. I am currently taking Humira which I have say has giving me the best quality of life I can remember for a long time :-). The question I have is that I have recently broken my wrist and had plate attached. Humira was advised to be stopped whilst wound was healing, but I am worried about continuing treatment, my main concern is that will it slow down the bone healing process? Tha reason I ask this is because Humira ( TNF- inibitors ) stop or slow joints etc fusing together, which in my opinion is a natural process in bone healing after fracture/break.

Thanks for any answers in advance  Gavin


p.s I know this is a RA site, but on my searching it came the closest to answering my question.

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Answers (1)
Lene Andersen, Health Guide
5/21/10 10:56am

Yes, we specialize in RA, but we do have a number of people who have AS, so I'll do my best.  We are planning to have more AS content, so if you're up to it, would you mind telling me a bit about what would be helpful information for us to have?


The processes involved in healing a fracture and a joint fusing due to various forms of arthritis is due entirely to different things. A bone knitting back together is a natural healing process, whereas a joint fusing due to arthritis is very definitely not. I suspect that it was recommended that you skip Humira while you heal due to the possibility of infection -as is medication is an immunosuppressant, you would be more vulnerable to infection, with which would be a very bad idea to happen in the bone. I would definitely recommend that you contact the doctor treating your AS or your surgeon to get more information.


Good luck! Please let us know how things go?

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By Impulze, Community Member— Last Modified: 05/23/11, First Published: 05/19/10