I have had severe joint pain in the past with positive RA Factors. This past year and a half the pain has been minimal and easier to deal with - I only take a Lorcet in the evening (anti-inflamitories do not help). My rheumatologist decided to get more aggressive before the disease does and put me on Plaquenil. I have taken eight doses and my joint pain seems to be much worse along with mood swings. Is this normal until my body adjusts?




