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The older biologics, Enbrel and Humira, have a longer history to judge their safety profile and effectiveness but the saftey and effectiveness profiles of the newer biologics are similar in the testing done. There has been very little testing done to judge one biologic against another and for many people, that wouldn't be valuble information anyway since what works for one person doesn't work for another. What would be really good to know is which biologic will work best for you so you didn't have to choose blindly. They are working on that but have a ways to go.
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