Monday, July 06, 2009 CJE4491 asks

Q: Methotrexate and liver function?

I was told to stop taking methotrexate after five months because of a "bad" liver function reading.  I don't drink alcohol at all.  Is it likely that the cessation of methotrexate is a temporary thing or does one poor blood test result result in a permenant avoidance?  I think the Meth was beginning to help.  Any info is appreciated.

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7/ 6/09 9:02pm

i was on methotrexate for about 6 weeks and when my liver enzymes hit 170 or so, i was taken off it immediately.  during that time, i was sooooo tired and fell twice because had trouble lifting my legs.  those are the signs of liver trouble.  so, we did a sonogram on my liver and check for all hepatitis, and all came back ok.  i switched doctors and new doc said to just leave it alone and the liver will heal itself, which it did.  numbers got back to normal in less than 3 months.  it was the methotrexate.  i, too, do not drink, hardly at all.

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By CJE4491— Last Modified: 12/24/10, First Published: 07/06/09