Sunday, October 05, 2008 Kansas, Community Member, asks

Q: Has anyone tried taking Enbrel 50 mg every other week instead of weekly?

Knowing the side effects, of which I'm feeling several in my 9th treatment week, was wondering why they don't even offer as a choice taking either 25mg per week instead of 50 mg  OR 50 mg every other week?  Couldn't that be enough to help some sufferers , while also lessening the side effect risk?

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Answers (7)
Hope, Community Member
7/ 7/10 7:41am

I take 50mg twice weekly and see no side effects.  What side effects are you seeing?  I have tried to cut down to once a week and everything swells right up and i can't walk.

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murphy, Community Member
7/17/10 4:26pm

I have experienced no other negative side effect of taking enbrel 50 other than that my semen has turned a dirty brown colour.Has any other male had a similar experience?

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srustin1, Community Member
10/ 5/08 8:42pm

Kansas,

 I'm like you, i was and still is getting the side affects.  I didn't at first but now I am. I started taking it every 2 weeks and now I take it every 3-4 weeks.  My Dr. don't like it but it's the only med that helps me. I want to keep taking it so for now this is the way it is.  I think I seen or read that Enbrel don't stop the progression of RA, no kiddding I could of told them that. When Enbrel first came out I started to gain weight so i told my Dr. and he said because of my eating habits, not! I said no way. Guess what now that's 1 of the side effects. Drs, need to listen to paitents. And for other meds I  refuse to take methrotrexate. It made me forget and make my skin smell. no thanks

I hope this helps.

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debbie, Community Member
10/25/08 1:26pm

50mg didnt work for me  had 2 injections a week of 25mg works alot better  but had nose bleeds every day for 4 years had to come off it in the end because i am anaemic

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Casiesea, Community Member
3/ 4/09 3:42pm

I have been on Enbrel 50 mg for about 9 months. I went to the dr yesterday and am being taken off because of bad nose/gums bleeding. Well, that and the fact that it stopped working. PA said that she sees "significant progression" of RA. Funny, I saw the actual doctor in January and he didn't think so.  Now they want me to go on Orencia, one of the IV meds! I really don't understand why i can't try another tnf inhibitor! 6 months ago the dr told me my RA was mild (the fatigue and symptoms certainly aren't!!!!).

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Casiesea, Community Member
3/ 4/09 3:42pm

I have been on Enbrel 50 mg for about 9 months. I went to the dr yesterday and am being taken off because of bad nose/gums bleeding. Well, that and the fact that it stopped working. PA said that she sees "significant progression" of RA. Funny, I saw the actual doctor in January and he didn't think so.  Now they want me to go on Orencia, one of the IV meds! I really don't understand why i can't try another tnf inhibitor! 6 months ago the dr told me my RA was mild (the fatigue and symptoms certainly aren't!!!!).

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Momrocks, Community Member
6/25/09 9:25pm

I was just prescribed this medicatlon and I'm taking 25 mg twice weekly Dr prefers it and said side effects were less this way. Not sure, just did my 2nd injection this week. Time will tell about the side effects.

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murphy, Community Member
7/ 7/10 6:57am

I am male and inject enbrel 50 once a week.Has any man who has been prescribed enbrel 50mgs,noticed any discolouration in their seminal fluid ejaculate?

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By Kansas, Community Member— Last Modified: 11/07/12, First Published: 10/05/08