I am a 25 year old female with some pretty specific RA positive results/symptoms (joint swelling, RF, and CCP); however, I have also recently tested positive for anti-Jo1 and Histone Ab, as well as having a low glucose count.  I read that anti-Jo1 was only present in polymyositis, and Histone Ab was positive in lupus.  Is it possible I was misdiagnosed with Rheumatoid Arthritis 7 years ago?  Originally they said I tested positive for RA and Lupus, but later decided to treat for RA only...

Doctors have prescribed many different RA medications (Methotrexate, Cimzia, Simponi, Humira, Enbrel to treat this with the only one providing any relief being Prednisone and possibly Sulfasalazine (I am FAR from walking normally even on 50+MG Prednisone).  My two middle fingers are swollen (right middle finger far moreso than left), my right wrist only has a very limited range of motion (I cannot bend it backwards), and my right knee only creates much pain when walking, etc. (I was recently told by rheumatologist that there seems to be ligament damage); however, they have both been swollen in the past with the right knee having always been far more swollen than the left.  My feet rarely if ever exhibit swelling or pain these days, nor did they at the time of my diagnosis; however, occasionally in times past there have been tremendous amounts of swelling in my foot or feet to the point where I could not fit into a pair of shoes, but nothing has been consistent over the last 7 years.  I also frequently but inconsitently experience a sharp electrical pain on the right side of the back of my neck upon sudden movement. 

My other current or past medical issues includes: daily headaches; daily fatigue; several cases of shingles; non-itchy, slightly raised spotty redness on chest, neck and bottom/back of ears; redness on chest after sex; possible early miscarriages; iritis; ADD/ADHD; disorientation; difficulty concentrating/staying focused; bipolar disorder; a fast and aggressive pulse paired with light-headedness, shortness of breath, tightness of chest, and leg muscle weakness (similar to that which occurs if one is very sick with diarrhea) occurring anywhere from twice daily to once every two months with episode durations of as little as thirty seconds to more or less than fifteen minutes in both stressful and non-stressful times (I have never received official diagnosis for this, as it has never occurred while under a doctor's direct observation); occasional "cuts" or sores around fingernails or toenails that blister and have taken up to 6+ months to heal; and more recently, blood from the rectal area (more obviously seen during "that time of the month".  Additionally, as a baby I had a severe reaction to the Pertussin in DPT shot resulting in seizure, incubation and spinal tap.

I have been on Prednisone and Methotrexate for 7 years, so other symptoms may be masked.

I have likely forgotten a great deal of other things, but please feel free to ask me if you think you need more information to help me.  You can email me at AMarieWright@MSN.com - I only have one body, and mine is already fifty years worse off than it should be... I have the body of a 75 year old, but I am only 25 years of age. :(