Hi- I just found this site  looking for information about humira. My  13 year old daughter  was diagnosed  with JRA a year and a half ago and we have been working hard with her doctors to find what works. My  daughter  was on enbrel for  6 months with good results  along with methotrxate but then it stopped working as well so her doctor put her on Humira.  She' had 2 doses with no relief.  She is so much worse, having daily flares.  She can't do  the things she was able to do on the enbrel.   I am trying to find out how much longer it'll be until it starts being effective.   She frustrated and angry.  She's been taking prednisone for 2 weeks to help  carry her through until the humira kicks in, but we don't want her on it for long.  She's having lots of flares, pain, fatigue even on prednisone. I don't know how long we should make her wait to see if humira will work and how can we tell if she's taking prednisone. She's being robbed of her youth as we  struggle to find solutions  that will help her.