I am 37 and was diagnosed in July after symptoms started presenting themselves at the end of January. I was a runner, super healthy and in great shape. I guess taking care of yourself doesn't count for much these days. :(   I was on MTX 20mg and 5mg Pred, but it wasn't cutting it - though I did feel a ton better. I started on Humira a little over a month ago and had my 3rd shot 3 days ago. I felt huge results the morning after my first shot. My pain simply almost vanished. My hands didn't hurt or anything. I couldn't believe it. I tried to wean off the prednisone a couple weeks latter, but could feel the pain coming back so I went back up to 5 mg 1x/day. Right now I can feel it in my elbows a bit, but my hands are looking great and I am back to running again. I am super out of shape now, but have been able to run with little walking a little over 3 miles 3x a week with now pain. Hopefully it just keeps working so that I can get off the prednisone and wean down on the MTX.