I am a 26 year old mother of three. I recently was referred to a rheumatologist for my joint pain, and hyper-mobility. My RH and ANA were negative, but all of the tests for inflamation were high, and to the extreme surprise of my rheumatologist My anti-CCP test came back a very high positive meaning that I for sure have RA, and it is going to be very aggressive. I also have a vitamin D deficiency, and she referred me to a geneticist for diagnosing the hyper-mobility. I strongly suspect that I have a condition called Ehlers-Danlos syndrome which means that my collagen is not made properly, and my connective tissues are very weak allowing my joints to extend way past the normal range of motion. I have a host of medical problems caused by these three conditions. The worst is the fact that I have so much pain, and the Rheum and my MD both refuse to prescribe anything for it due to my stomach issues from ibuprofen overuse. I am currently on Plaquenil, and over the counter vitamin D. My main question that my rheumatologist just couldn't answer: How are the EDS and RA going to interact with each other. Has anyone heard of someone having both? EDS is extremely rare so I am asking this question on the EDS site also. I want whatever info I can get.