This summer has been brutal, but my heat tolerance has really changed this year. I'm thinking it is one of the meds I am taking. I was outside ten or fifteen minutes tonight. My husband and I were putting a shade tarp over our little garden. The sweat was pouring off of me, in my eyes, and it was literally dripping from my hair. I looked as though I had just gotten out of the shower. I started to feel sick, so I came in and peeled my clothes off. Ugh. Think MTX could cause this increase in heat intolerance and sweating?
Q: The heat is really getting to me this year. Does MTX cause one to sweat a lot in the heat?
Answers (6)
7/26/11 8:21am
7/27/11 6:28am
HI V yes i think we need to have a second home where its nice during the summer. i have noticed that when we get floods during the spring that means that we are going to have a very hot an very dry summer. last year july was a little hot for about 2 weeks the august was a record for been cool. times like this now i wish i worked in a/c building thought would never say that
7/27/11 7:46am
Thank you for your comment, Suzzy. At least I know I am not alone. I was outside for 15 minutes last night watering flowers, and the sweat just poured off of me. It is unreal. I have never experienced anything like it. I drink a lot of water. Guess that is a good thing. I really think the MTX is the cause of this, because I was taking NSAIDs and bp meds before and didn't sweat like this until I started taking MTX. Oh, my.........I'm afraid I have a serious intolerance to heat. It absolutely wears me out! You be careful out in the sun, Suzzy. My doc recommends Neutrogena sun block, and I love it. It is SPF 70, and goes on dry and doesn't make you feel "sticky". Drink lots of water, Suzzy. Take care! V
7/28/11 8:59pm
im glad im not on mtx anymore that stuf was to weird for me an i sure wasnt myself. i hope you well get better on it. this is the first summer i wanna throw my white flag in. i know im not me no more i caint do the things i used to an realizing it is very hard to do.i stayed up it 8 tonite an im so tired i havent even got my work clothes changed yet. i just might sleep with them on lol . my garden is almost durned up my grass has been dead for a month now which is good on my part i stay in one room of my house when im home so the rest stays clean. and i dont even feel like cleaning that room. when i started to see my rheumy an he started talking about these meds before i got on them i cleaned my house inside an out just to be on the safe side of what i could do an im so glad i did.
7/28/11 11:06am
I had the sweating/drenching/heat intolerance stuff going on before taking the metho. But I did notice that after I started taking it, my sweating episodes picked up and are really bad for a few days after I take my pills. Actually, my sweating episodes happen intermittently throughout the day and night and wake me up from my sleep. And, it's just pure torture going outside - it makes it really bad.
7/28/11 6:09pm
I also seem to sweat a lot more than I used to, but I didn't even consider a connection to MTX until reading these posts. This side effect wasn't listed in my drug reference book. However, I found the following information on Drugs.com regarding MTS: "Other less common reactions included ........sweating,........"
7/28/11 9:53pm
WOW! I would have never put the connection together but I think you have may something here. I too sweat profusely when I'm gardening, washing dishes, or working at the horse farm. I may have a "tummy roll" but I see myself as fit so I can't figure out why I sweat so bad. It is just really embarrasing! The thing is that I am like this even in the coolness of the morning....sooo just might be the darn meds! Always one more thing to have to deal with.
7/28/11 11:21pm
Some of the side effects of Methotrexate are sweats, chills, and rashes. Summertime adds to the effect. I don't think you are imagining it, but it could also be because you were exerting yourself more than normal as well. I find I frequently have night sweats and I am past menopause so I am assuming it is the drugs. I hope this helps. p.s. Short term memory loss is also a side effect of MTX. I found this out after a CAT scan for alzheimers. Oh joy:-) I hope this helps. Deana
7/29/11 7:08pm
Oh, shucks! I didn't know about the side effect of short-term memory loss. I used to have a memory like a steel trap. I started a new job about 3 months after starting MTX, and found that I didn't remember things as well. I attributed it to the stress of the new job. Now 2 1/2 years later, I still have the stress (even more) and still forget some things.
7/29/11 7:45pm
Oh, geez. My shot-term memory isn't nearly like it used to be. I was attributing that to getting old! 
7/29/11 7:44pm
I have night sweats, too, Deana. Actually, I was sweating like crazy just sitting still outside, so it wasn't from exertion, either. Must be the darn meds.
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Not a problem, Leslie. I just realized I had RA before I started taking the MTX, and I didn't sweat like this. Not a very lady-like term, I know, but persperation does NOT describe what I am talking about! LOL I have water pouring off of me if I am outside for five minutes. Of ocurse it is hot and humid here, and has been for weeks, but this is ridiculous. I had a dentist appt this morning, and I mentioned it to him. He thinks it is the MTX. Will be interesting to see if anyone else has the same problem.
Thanks!
V