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RA by itself should not impact your fertility, although, as you've found out, certain medications like methotrexate, do. I did a bit of research regarding prednisone and couldn't find much indicating that the drug prevents conception, although I did find a reference to it possibly impacting the regularity of your menstrual cycle, which can make becoming pregnant more challenging. Is your cycle regular? If you're not sure, you can use a basal thermometer to find out when you're ovulating. I wouldn't recommend stopping your prednisone, though, as it's important to be as healthy as possible when you're preparing for baby and that includes keeping your RA controlled. If you're concerned, go back to your rheumatologist and ask questions until you're comfortable.   Becoming pregnant can take a while, regardless of your health status. It is recommended that if you are under 35, you try to get pregnant for a year before seeing a doctor, over 35, the recommendation is six months. Depending on how impatient you are, you might want to give it a go for six months of unprotected sex 2-3 times a week and if you're still not pregnant by early next year, make an appointment to see your doctor. There are many fertility related sites on the Internet that can give you more tips.