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I'm on just Humira. Meth didn't help me at all and I've tried the Prednisone, but my doc. doesn't want me to take it for very long periods of time so I got off it as well. I went through a really hard few months with no meds at all trying to get myself cleared of all the meds, then I couldn't take the pain anymore and I tried Humira. I've had only 2 injections so far, but the difference is TREMENDOUS. I can move again. Its amazing stuff. I'm vacationing in Arizona and plan to try out a little "fake and bake" tanning before I go. I think if you wear sunscreen and try not to overdue, it will be fine. But there is an increase risk of melanoma with taking Humira. But I grew up in Arizona originally and baked myself crazy all my life...so I think I already have that risk anyway. Good luck.