hello, it stings a little!! i just started myself, i have had three shots so far. i took them all in the arm. i have had no problems. it has been the only thing to ease the pain other than the pred.the only dide effect i have had is a little acid reflux. i think i will continue taking them in the arm, although i do swich arms every week. good luck!

I was on Enbrel for 9 yrs. I didn't really have any side effects from it. I think I liked the injection better with the syringe instead of the sure click. It seemed the sure click hurt a bit more. You just click it and it will inject on its own. Kind of a cool set up! A least when I would use the syringe I could stop for a second if I needed to. It just took me a while to get brave enough to do it myself. :-) After a while not too bad. I always injected in my stomach. It seemed if I squeezed the fat harder it hurt less or even not at all. By the time I started Enbrel I didn't have a good range of motion so injecting in my arm was not an option.