I am too have RA since I was 32 yrs old. I am now 48. I see your concen regarding your wife running out of her meds early. I would call her dr. & explain your concerns. She is obviously taking too much medication. Her dr. will keep your call confidential & will appreciate you alerting him of this. As for her always sleeping, when I was first diagnosed, that is all I wanted to do. RA takes a toll on the immune system.  It makes you very tired. After I was regulated properly on my meds, I started to feel somewhat better and forced myself to get out of bed & get dressed in the morning. There is nothing wrong with giving in and taking a nap in the afternoon if your body is calling for it, but it is important to get up and get moving. The best thing for RA is to keep moving.  I still do here and there lay down in the afternoon. If I get tired I give into it because if I don't, I will just end up hurting more. Try speaking to her dr. & go with your wife to her next appt. Good luck to you both & God Bless. It will get better.