Just had my first Simponi Shot on Tuesday. Any idea how long it takes to really work? (Yeah - I know I am under 48 hours from when I had the shot, but I want it to work so much... I'm becoming truly neurotic from all the pain!! 
)
I think Simponi is helping a little already. My left hand, knees, shoulders are less bad and I slept better last night - still stressing about pain though.
Pink
(On MTX - 25 subq/ wk, Folic A. 3mg/day, HCQ 400/day, Celebrex 400/day and now Simponi 50mg/month)
Hi, Pink,
Unfortunatley, there is not one easy answer to your question. Most RA meds take a while to work...3 months, generally. On the other hand, some people see results much quicker than that. We all react to meds differently. I know after my first Orencia infusion, I felt better and my swelling decreased. I hope Simponi works well for you. Let us know how you are doing.
Blessings,
V
V is right. medications usually take 2-3 months to really kick in, but the Biologics do have a habit of every now and again letting their presence be known sooner than that. It often starts with things feeling just a bit better, getting more energy and before you know it, every day brings a little more. I hope when you're feeling is the start of something wonderful.
Please keep us posted?
I like the way you put that "a habit of ...letting their presence be known" that is exactly how I feel! Thanks for the encouragement. I am hoping that every day will bring more and more. I just am so ready for life - if only my body would agree.
Pink
I like my name too - I have a carved moose above my computer and he is always smiling at me so "Pink Princess" evolved to include him...:)
I love getting a peak into our community members' lives - now I can imagine you at the computer with a moose looking over you. 
PS love your username!
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V-
Thanks for the response! It is so hard to wait. I have seen some improvements already, but I just so want to be more normal that I am finding myself struggling to remember to be grateful for improvements made. I like the Simponi so far. I still need my MTX 2x a week because i notice an uptick in pain just before my hot, but I have been more functional in the past 3 weeks than I have been for the past 8 months. I hope the upward trend continues.
Thanks again - Pink