Absolutely. I was on Enbrel for about 2 years, and I went to the ER with eye pain, and one of the nurses almost panicked when she saw the list of medications I was taking, because she had a friend who had a bad reaction to Enbrel which left her temporarily blind. It's apparently rare, but if it can happen, I'm sure your day-to-day eyesight would probably be affected as well. The nurse's friend had an honest allergic reaction, so I don't think there's any reason to panic for you, but I would mention it to your rheumatologist and your eye doctor. I'm on Humira now, and that was my first complaint, the shots are drying my eyes out badly and often it looks like there's a fog preventing me from seeing clearly. I've been told this is directly linked to the Humira and we're talking about what can be done and the cost since OTC eye drops don't help. Your eye doctor should be able to help you, if you speak with your rheumatologist and they tell you the common side effects linked to your eyesight. Arm yourself with that knowledge before visiting the eye doctor. You wouldn't believe how much it helps to go in with partial answers for them to bounce off of.