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Hi, Shahida,   Methotrexate is a DMARD used to slow down or stop the joint damage caused by RA.  We can't know for sure what will happen if you stop taking it, but I can tell you that most of the people I know who stop MTX without going on another DMARD, usually flare after a short period of time.  Is there some reason you want to stop the MTX?  There are other DMARDs out there.  I would suggest talking this over with your doctor.   Best Wishes, V
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