from what you say in your question and your replies to answers, it sounds as if you are on a combination therapy of Imuran and methotrexate. The reason you feel good is because of the medication. RA is a chronic autoimmune disease that can be controlled by medication. You may very well be in remission, but that is because of the medication. If you stop taking medication, the RA will come back. Is it possible that the Imuran alone would be able to deal with your RA? Maybe, but that's something you need to discuss with your rheumatologist. Most likely, it is a combination of the two medications that is preventing your RA from taking over.   You should also be aware that if you and your rheumatologist decide that you could try stopping methotrexate, it is something that should be done very slowly over long periods of time. If you stop methotrexate "cold turkey" it usually triggers a huge flare. You should also be aware that if you stop the medication and your RA comes back, you don't always respond as well to that particular medication again. These are all considerations you need to think about when look at changing treatment options. My best advice to you is a lot like the old saying about "don't fix it if it ain't broken." You are one of the lucky ones who have found a treatment that suppresses your RA so you can focus on your life. I would be hesitant to change anything that's working. However, I do recommend that you speak to your rheumatologist about the issue.