I was diagnosed with RA in December, and was prescribed diclofenac. It helped greatly with the pain, but my liver enzymes have been going up steadily since then even after lowering the dosage. I'm currently off all medications.
I have an appointment to see my rheumatologist on Thursday. What drugs are available that aren't metabolized by the liver?
I think all tablet form of drugs can and do affect the liver as they all pass thru the liver.
I cannot take most of the rheumatoid drugs or any of the injectables for one reason or another.
However I have been sucessfully taking the anti-inflammatory Orudis 200 mg. (Ketaprophen) for 16 yrs. without any side effects and it works very vey well. I just have to take Pariet (anti-ulcer) drug with it as it can and does give ulcers. I also take between 2-5 mg prednisolone.
Take a liver cleansing tablet that has Milk thistle in particular but some also have dandelion and arichoke too.
Or try another anti-inflammatory. We are all affected differently What works for one does not always work for another.
There is a company coming up with drug patches and instead of having metal in the patch like the nicotine patches they use Vitamin E. The company is Phosphagenics and should have these available by end this year. This would be great for those of us who cannot take the tablets and injections as these patches are also slow release probably easier on the body system.
Thanks for all the responses. Because of my most recent lab results, the rheum. thinks that I may have had some liver damage from a previous viral infection. He's suggesting a liver biopsy, and I go to see my regular doc next week. I'll be sure to ask her about these supplements that help the liver.
i've had 2 liver biopsys in the past year - thank god i won't have to have another for 5 years if i can stay off most of the prescriptions!!!
they aren't as bad as it sounds - only hurts for a little while.
All best of luck Jill, and I really feel for you. I'm on Enbrel, 2 anti-depressants, a sleeping aid, and pain meds. They all hurt the liver. Any drug you take, any vitamin you take, any energy drink you drink, any vodka collins (etc), any caffiene, is processed in your liver. There's no escape. There's only the choice between drugs that are hard and less hard on the liver, and any doctor that tells you different is not well educated or does not have a complete viewpoint.
What I do, since I need to be on so many meds, is do a 3 day water fast once a month. It's pretty easy, and incredibly good for anyone, but especially for those of us with autoimmune disorders. It gets rid of toxins, cleans and rests the liver and kidneys, and relieves inflammation.
Also, I take supplements that are supportive and cleansing for the liver. This is really important, and doctors will either deny it or sometimes act contempuously because it's "not science." (yes, it is.)
The one I take, though there are many, is called Daily Balancer, by Wellness Resources (you can find their website online, I promise I don't work for them, I just like their supplements and loads of info about scientific studies and the like). It has, among other scientific things, milk thystle (detoxes the liver) and dandelion (supports the kidneys). These things are well known, safe, and really help.
Mention them to your doctor, and of course be careful since I don't know you and don't know the specifics of your illness or treatment, and I'm not a doctor (and neither do I play one of TV). But these things have helped me a lot. I've been on heavy meds for 7 years now, and my so far my liver is testing out fine.
All best to you truly,
An old doctor told me a long time ago "Drink a full glas of water with every pill you have to take". I think that old man got it right. This was long before computers, MRIs, SUVs, etc.