can cognitive disturbances from taking methotrexate be reversed.
Many of the immunosuppressants can cause mental fuzziness around the time of the dose, including some processing difficulties with getting things from short-term memory into long-term memory Usually, this can be managed by a slow day or two and carrying a notebook and pen. however, I'm not sure if you're talking about mental fuzziness that can be managed relatively easily and which can be considered an acceptable side effect in light of the beneficial effects of the medication or actual significant memory loss. I would therefore recommend that you speak to your doctor.
This is new for me. I'm not even aware that methotrexate could be the cause of memory loss. But I do know that cognitive fatigue (and accompanying memory difficulties) can be associated with RA itself.
So I don't know the answer to your question, but I do wish you the best. Hope you are feeling well.