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Thank you for your answers. Every so often I'll get soreness in my thumb and think ... this is it ... this is the first sign. My father had it really really bad. He was diagnoised at about 40 because his neck was always bothering him. I watched him go from someone who was physically active to someone who could hardly do anything. He died last March at 62. The RA affected his lungs and he then developed a secondary condition called amyloidosis which affected his kidneys. It was really horrible. He came to live with me for the last two years of his life. He did find and amazing doctor though in NYC MT Sanai medical center. But by the time he found the doctor he was too far along to really reverse anything. The RA made the amyloid worse and the only way to stop the amyloid was to stop the RA but the meds for the RA compromised his immune system and he was very prone to lung infections......    I do have a friend though that I work with who was diagnoised with RA had it for a few years and has been in remission for the last 10 years. So that happend too. Thank you again. Meg